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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76ba10d375cdf006444b9aad6f0084d9c31350fb8e4cb74508c90a04e0c05fc0' 
  AND token = 'sJXn2DoO0aOtqS2/NsVLEOykxNfhiUZ11ZRu3wFUpP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}