SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b380f2cc3aa075b6babb71f3c278f908045a8b1fd7b571629b91e85eba038d6' 
  AND token = 'yfw3HxY6pNn/XIJzL9LNsb5WkTrcYioyjz9sGpPkbMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}