SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b3912fdb48a529c21961ad7f2802c79254eac5d84fb25821308122255dcf45' 
  AND token = 'xx+71dq5zNVIPcA8Eh7+RcTMCMnHfiM0CyMq6Xspfu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}