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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1059dc45da7bf1a876a7b7b308c45ef975f5b3a3e081bf90d5487a03574398f' 
  AND token = 'q7vynK1OljKg1+mp/ZAP6nSdUzV1CrHOkUR13rLjHLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}