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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8097f1dda521c31748ecc5ff9f54f5f853dc67427da0f7808956a4e93552f03f' 
  AND token = 'oCr4LIxP6AvfTSxSXYlBIMlJ3rbUVAZ5Kaj5rvThc8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}