SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c5b94de3f6f6d43f4acf25472aaee3634f927b1ffc485be465decdd0b9f455' 
  AND token = '+Dz1A3inCn7xkAZiEIzFJJqC4bgbcCTOxH10M0PFJo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}