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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f27a93f776e68eb04d14385053d58b7f95c2fc0395e185943a9824e200e3e17' 
  AND token = 'DEPCB0gGH7PKy2L0xqQjlyQNCEVt7gj4RN1XTdG/ihc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}