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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd878aaac04c4e65737e313e5359dde36fa6139b84c850dd174c95273fb9a5db8' 
  AND token = 'ZAiwpRkahWE0d1vsyGLuHFNmXk4uq9QglO+4OrA5dtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}