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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f62bbb1435b544eca97c89d3fc4546d30fdd9875b4b9e58ff432660a940dcbe5' 
  AND token = 'FTcWMZy+d2HPnQHzLR8kZ8wCsZJHhuIV6pnOozM16PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}