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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9353c1810d0cbe54fee113e03985800387e8270601fee8696bcc3209b158a8' 
  AND token = '/S++s6clFeYdns0oJME1lxBP5pGvPEipN89CaQE/53k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}