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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab28796644586295644e6bea13404d61da615ac93f5b2aa2cf5d50851b45fd7c' 
  AND token = 'V0p8aNjwV9T7an87lT/VdfTDvlqtwynbWFJhODbxqrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}