SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc44ea2db2ebbfb632cf122bf6835aab0e1553d815b91fe26f5c3844fa0aa222' 
  AND token = 'WzztJSofk8zaazUzcCJfSITrvyrWBnS1nllkyVQtbhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}