SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456320be4ce53182e0b7350cbe07a4931c0bb8d0de15895b02ae032f847f027c' 
  AND token = 'fpSBDpOgvzZYNzWdrEwSZ8Xqt8YG2QPaTSb2+B8Hir0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}