SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14bd3e71da8c360901b621a4d2a4b1261f1cd9c57ed9bb27d8d278d4f32327ae' 
  AND token = 'j3NGR8iY+4Oz79xhwrKBpIY+7RLUrOD3wO3NvWaRZq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}