SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22662743e5770b8e7c16ac22875bae71f4baae018fd628df17c694eb02f535a9' 
  AND token = 'QXokytCisz/eJOx2kwbKHeGyyEuWghaPrBBcV6WaxPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}