SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37236aae7b5fd1e0702dd609ad009d4797f4102fe8abdbd54181e4e37340bd4a' 
  AND token = 'OOwxzHXqTNS/7VKvEs6TEvuQ4r8LZQCwYgfQquiAexg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}