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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44974359d1e78bcc5a868a3c6b36a99efe6c5aaf60592d39b276d166d3d350a' 
  AND token = 'nUVCatQNept94i2IcE3Whb1RbYXhoCqRP2qjzNr00CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}