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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7ddc90a9c7094cc5340f8a3dc59b7ca2db24105a45f40775af23369ef50f21' 
  AND token = 'fF/byq82zSj+BYheOTZ2tESsA6LNJqSZlRmas+bsB0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}