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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2afd94f9e9d9575d5580d859e4eb2d311da2b0be59bf1117a2cbe2be59db66df' 
  AND token = 'uQD1HoRs2FaGFlLbO4pyiv0YkWufJKzgrMHftMW5z+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}