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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10eb019634c382249149708b49dd1c52b5899f9d628fed86a62b7144f7b54b18' 
  AND token = 'nfZbi0Ucju+erbYfElb65Onk/+I9aLgVB7l88yF4yng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}