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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f00ef54ad5162935e33aff2981c8381f82a458922729917bc3081e168c002b38' 
  AND token = 'AP32HkjH6lMu03dmvhE0+JDujW5RbZrpWVYJH6LudZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}