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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae280770abb12662a9a4907e503a12496e8949a21d7ea8e724966ed8bdc9f38b' 
  AND token = 'R+Jw3Y5futHL0pKnIc3yrM/FsEiP29L7acKXv4WtLGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}