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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5911788b84bad4e957b5236f8a46c5907fb6cb67b7faa3445d9a4f8fb63c366a' 
  AND token = 'pjeAyD15yr5JdeYbVLMCZLXCMaU0ABlPgDeXOjV0KLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}