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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50730ab4343684fb4d31e8cb0de6b1189f3ee6fcde135cd5417c96c34b5e81b2' 
  AND token = 'CWxLXVG3V8erFPp3BlbXdx1KUXyvtoQvGL1+ZwtL3GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}