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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ebd2cc510b72fd52c8d7170a023f16c3e5f1985ff788b54f0b7f33d9732176' 
  AND token = 'hin1kWekskaL2H9yuyMpUZkoX+EcMkWRxo4mnB6dt0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}