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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2eb26720610b5ee3dfef088e26b2ac1a03a5b078117ec3e4acb56f46f5550c4' 
  AND token = 'DIu0yeE1D9uXe8RBG4rpTqNYD3jk1vlVOfqvZf59WCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}