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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e765012a702519b7d48d7b8dc18b58c8f1c1974db862d7a1fec2ff48539d53' 
  AND token = 'rjLPkjOMwjLCugKP0XY7iV46iPMyj77no7QMOraD4qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}