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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bac188d68dacb7be078552871c152772b2c37f83fbfdb1b1945168a0bde5dc7' 
  AND token = '4HF5XlFDgp1fK5VCm7ilrlPUFknt8Cs5UrKsLvwftHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}