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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be1134f1dc909129590733032061f11c00407285564ca8128b8994f4e7daf8e3' 
  AND token = 'e2aYr/cgXtlv0emOjnWfYXR6LKXJ4jT1U4UmB4dkTJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}