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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22a7297b45fc7fffea3e1cf88db3faa91131b60aba4d0da6bade85809997aef' 
  AND token = 'pCsUXsCZHhFfjPtRh4tHCNgdF3lEdQf4NE37iKW42ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}