SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4168b8706178d0173cbdf48ea1019923abfe096b937759e76f0ca1a388d544d' 
  AND token = 'ST0UzTr7Yd1N22a8PZ1bkLr50gbGejaXAZv55I01cV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}