SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4ebc134462e50b25636f846c5040b8145b9f78827d85ae07e3c5e51d3da4ae' 
  AND token = 'tZE/24qGzFG7WaW6TJ0CWhre1h3ELBdVv6gY3+QZvfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}