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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaf6eb90410f1ca46714c9cdc89d9dd3a6b16e8e36c710a58380802e3b253fd5' 
  AND token = 'OzWeGZyweExoneTqI/lz1XxjMdvg84yMd4d9zi/ngP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}