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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72015a0c055e291097f8a6cc1d3635eda1a89eb2ba113e05727d08461f713e97' 
  AND token = 'MPtyPW1o3rXTagsIJQY7A3ocIvr5+pdtlcCBhKbGK9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}