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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a76682921abcbbb70ddbaa8debd865a63bdb540e67332dc358e7f291cc4bec2' 
  AND token = 'S5N1ZOMQEnZ5JTMEc3e7VdCZ2fPawvgZJaDlxmuq9yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}