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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cc48403e71d13f60f68a058f425acf983bfebdf87f75cc0ccac850f873f492' 
  AND token = 'cFC53Zz4+pF58OITnt+j+4ZLGy18nE/VxKjlMlxLnJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}