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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b966ba9ebc7879b1e2d365e311114b7e3b45f0cd9b9d3a67385936e038679549' 
  AND token = 'QyV4Dlv1yM7By+aLUGw3oEHBFqfp95k7V3b1n0WIsNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}