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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e0b7dfd8495c1cf45502f32e0be7f6378419d6f20b601ced8c968ffdda1409' 
  AND token = 'D+yj6udCXdUW6Gq98lIG5Y3B49ZMJT6Axdu4ZJZLhc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}