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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6127bfe2db58f5176e84104cc0556d2090b34168439731ea4618c2766d3ccfb1' 
  AND token = 'VoLtunfBzc/ZmG31pH3AoJ4IJx4VxzcLW95h6/w37Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}