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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a8918e81db2ebe11085698e3a01c1b9381480c0836517dfd43d3f1528311b5' 
  AND token = 'vFZEeqrNZ/jT/oXRKotK3vLrQTaN7BYWd6w4LVPICas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}