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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3163a49371afe64db03cce74dda4b2032f3902b2490a6cd736e814ee4e31f15' 
  AND token = 'JrGGVkTgI0jd8D1R0CQgEuBWep07EfONnxpEEj/ZbJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}