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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7db4f4b1e3ccbb3d11415ebe6f89f10771540c5b78cb4cac0819f591ba66646' 
  AND token = 'WzyDBTZi54oRpJZEzpNrpF+DzQZDH2haBUDe7Ozl56s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}