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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2ec5ba1def138dbab7d7166f96011a6d3ee6d882e0bcc2c03d81e3eba2046a' 
  AND token = 'NB1037oZwzLCYNWqnAmPzRd5ebp296TeSzZg5LEBebo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}