SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1024d87608c33755e2215f0e9197fbbd3a29ab81c68ff1ffa0d6a9ef92bdc07' 
  AND token = 'FBKe9pmiVeV1XVdtr3XvuCxDZtvSj+5LMSYTA0V/XXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}