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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324b814a1991ca62ae2a0f804bf0b95e68f2718a27850ca26c4ac14c020009db' 
  AND token = 'higIn30XYAN+cpjlgQqIr0KmmdPYwIlL5N1cC0AJsDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}