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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657a3a11eb81fc451c65a2d468e4c0d4b013fc05a6da049752902af2a177c65a' 
  AND token = 'lWflV9bHWz3quwnzR3midsmBOHBYhf+ENkfkfkvo/9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}