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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708a5335d2a4dfa0a270fc2da0c9a0b61e5a824f8998398e0d9b8200ba64a01f' 
  AND token = 'UEhy6KuFERzbbN48ns3RcxppL1WGLnUiwLR6mB6BX6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}