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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0af601a798a1d4b276941a32daf32d77226a22643bedb33468bcc2a6166951b' 
  AND token = '6UipQ5QO05w/UBB0/FJ8lR3wwFHNm7sjbd/dAuwe38U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}