SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab2a7acd45ff980ad9a23c1565a8193b5ea370be1af8851666e6aede6c3fa46' 
  AND token = 'GekSeNBiX0pNTB4dtgJeuasAIMMH//SgQj/YDqXJh/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}