SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82655efa87dd13bc3185d6b49e95345bdd92d2eada3cb29e71e6ef060937d13d' 
  AND token = 'VS7w/ImSTM9ldfQt4RA1OXA+tt/GjCT8BmNTlikza18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}